Posts Tagged ‘Male Sex Hormones’
Androgen receptors are intracellular steroid receptors playing a key role in the hair growth process.
These receptors specifically bind the two types of androgens – testosterone and dihydrotestosterone (DHT). It allows the androgens to stimulate and regulate the development and maintenance of masculine characteristics in vertebrates.
In some cell types testosterone interacts directly with androgen receptors. In others, testosterone is converted by 5-alpha-reductase to DHT. The latter is an even more potent agonist for androgen receptor activation.
Examples for the first case are derivatives of the Wolffian duct.
Derivatives of the urogenital sinus, the urogenital tubercle, and hair follicles exemplify the second case.
Cause of androgenetic alopecia – Androgen receptors are at the center of androgenetic functions. And androgenetic functions are the cause of androgenetic alopecia or male pattern baldness.
The role of anti androgens
Anti androgens (a.k.a. androgen antagonist) are known for the solid guard they offer against the effects of androgens. Thus they play a key role in the androgenetic alopecia cure.
But what are anti androgens, in the first place?
The term to any of a group of hormone receptor antagonist compounds able to prevent or hinder the biologic effects of androgens (male sex hormones) on Normally Responsive Body Tissues.
How do they work?
The typical working style of the anti androgens is blocking the appropriate androgen receptors. They compete with one another for binding sites on the cell’s surface. Ultimately they obstruct the androgen’s pathway.
Uses of anti androgens
Anti androgens have a number of curative uses. They are used in various ways for androgen alopecia treatment. Apart from that, they have other curative applications as well.
Some of the other curative uses of anti androgens are as follows –
a.) Curing certain male sexual disorders b.) Use as anti neoplastic agents (anti tumor drugs) c.) Use as a palliative and for adjuvant and neoadjuvant hormonal therapy in prostate cancer d.) Treating hirsutism e.) Treatment of acne vulgaris- an inflammatory disease of the skin.
Administration of anti androgens among males
Administration of anti androgens in males is likely to slow down or stop the development of male secondary sex characteristics. In fact, it can even reverse them. It can also decrease accessory male sex organs activity and function.
This explains why anti-adnrogens are usually used in men only as a last resort.
Anti Androgen Withdrawal Response (AAWR)
It stands for the medical course that is taken when cancer cells adapt to feed on the anti androgens rather than on the androgen. This situation warrants a break for the anti androgen for some time.
This will lead to the starving of the cells thriving on anti androgens. It is a common syndrome among prostate cancer patients undergoing anti androgen therapy.
Anti androgen drugs
Some of the anti androgen drugs available in the market include the following –
Spironolactone (examples include Aldactone, Spiritone) – The primary use of this corticosteroid (a class of steroid hormone) is to treat low-renin hypertension, hypokalemia and Conn’s syndrome.
Hypokalemia refers to the inability to retain potassium sufficient for health. Conn’s syndrome stands for a symptom resulting into nonessential hypertension.
Cyproterone acetate (examples include Androcur, Climen, Diane 35, Ginette 35) – This potent anti androgen is used in problems related to female menstrual cycle, pregnancy, and embryogenesis of humans and other species.
Flutamide (Eulexin), Nilutamide (Anandron, Nilandron) and Bicalutamide (Casodex) – These non-steroidal pure anti androgens have Flutamide as the oldest of the lot. On the other hand Biculatamide is the newest. While Flutamide has many unwanted side effects, Biculatamide has few.
Ketoconazole (Nizoral) – It is a relatively weak anti androgen. It works against a variety of fungal infections. Its oral use can have side effects like serious liver damage.
Finasteride (examples include Proscar, Propecia) and Dutasteride (Avodart) – They prevent Testosterone from converting into DHT.
Androgen receptors play a key role in androgenetic alopecia by specifically binding the two types of androgens – testosterone and DHT. Anti androgens offer a solid guard against the effects of androgens. There are various anti androgen drugs available in the market.
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Hair loss also known as Baldness is a big worry to many people, both male and female. Baldness is not usually caused by a disease, but is related to aging, heredity, and testosterone. Hair loss usually develops gradually and may be patchy or diffuse. Some women also develop a particular pattern of hair loss due to genetics, age, and male hormones that tend to increase in women after menopause. The pattern is different from that of men.
Female pattern baldness involves a thinning throughout the scalp while the frontal hairline generally remains intact. Excessive hair loss can occur if any of the stages of hair growth become disrupted. For example, if follicles shut down instead of growing new hairs, there will be less hair on the head. Loss of hair at a very early age has become a common disorder these days. We loose 50 to 80 strands of hair per day. Do not get alarmed, this is quite normal. Unless there is some deficiency in diet, or ill health, lost hair is quickly replaced by new ones. Each hair grows between one quarter and one half inch each month.
Some men have areas on the scalp that are very sensitive to the male sex hormones that circulate in men’s blood. The hormones make the hair follicles – from which hair grows – shrink. Another reason might be interference with the formation of new hair cells at the root during the growing phase; this occurs with some anticancer drugs. Baldness is generally regarded as natural, and not a disease. So if a person decides they wish to try to get their hair back, they will probably have to pay for the lengthy, expensive procedure themselves. This hair loss usually can be helped by treatment thyroid disease. Hair loss may occur if male or female hormones, known as androgens and estrogens, are out of balance. Correcting the hormone imbalance may stop your hair loss.
Women can also suffer hair loss, especially those with many relatives who are also prone to losing their hair. Fungal infections of the scalp can cause hair loss in children. The infection is easily treated with antifungal medicines. If a medicine is causing your hair loss, your doctor may be able to prescribe a different medicine. Treatments for alopecia areata include injecting steroids into affected patches to stimulate hair growth. This is not practical for large areas. Other treatments, such as oral steroids or ultraviolet light therapy, are either toxic or impractical. In most mild cases, patients can comb over the affected areas.
Treatment For Hair Loss:
1. Styling hair to cover the areas with the most hair loss is effective for mild cases. Washing and styling the hair will not cause further hair loss.
2. Minoxidil is a liquid that you rub into your scalp twice daily to regrow hair and to prevent further loss.
3. Finasteride: A pill taken once daily that blocks the effects of testosterone on hair growth.
4. If adequate treatment is not available for your type of hair loss, you may consider trying different hairstyles or wigs, hairpieces, hair weaves or artificial hair replacement.
5. Surgical procedures like hair transplants can be useful for some women as well as men to “fill in” thinned-out areas.
Use the following essential oils for massage of hair to reduce hair loss: 1. Jojoba oil.
2. Roman Chamomile.
3. Lavender.
4. Rosemary.
5. Grapefruit.
6. Cedarwood.
Home made remedies for reducing the hair loss:
1. For nourishing your hair, apply coconut milk all over your scalp and massage it into the hair roots.
2. Massage almond oil on scalp 2-3 times a day, daily. This will stop further hair loss.
3. Make a shampoo by mixing 100 g each of amla, reetha, and shikakai and boil in two liters of water until the liquid reduces to half. Use this shampoo for your hair for at least one month. Your hair will become thick.
4. Lettuce is useful in preventing hair loss. A mixture of lettuce and spinach juice is believed to help the growth of hair if taken to the extent to half a litre a day.
5. The juice of alfalfa, in combination with equal quantities of carot and lettuce juice, taken daily, also helps the growth of hair to a remarkable extent.
6. Onion has also been found beneficial in patchy baldness. The affected part should be rubbed with onions morning and evening till it is red. It should be rubbed with honey afterwards.
Hair loss also known as Baldness is a big worry to many people, both male and female. Baldness is not usually caused by a disease, but is related to aging, heredity, and testosterone.
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Hair loss is a new problem for men’s in now the days. In social life men’s facing a lot of problem regarding hair loss problem. A lot of men today who suffer from hair loss are usually so intent on finding a solution, they will try almost anything. It’s not that they are looking for some fountain of youth. They are just tired of hair loss making them look ten to fifteen years older than they really are, and they are committed to doing something decisive and positive about it. By reading the advice on this article most people will at least be in a position to decide which hair loss treatment or hair loss product online, if any is suitable for them.
Why online Hair loss treatment
Hair loss treatment on online is the easiest, fasted and smartest way for male pattern baldness treatment. There are soo many products are available in market with cheap rate which may make you confuse. Hair is shows the beauty of you, so don’t treat it with some cheap rated medicine or some other products. One of the trusted ways for hair loss treatment is online hair loss treatment. On Online treatment you should go by some following steps. First you should console with doctor on online. Then you should fill up a medical report page, where you have to give the details of your past health report. Our doctor will check the report, after they go through it they will tell you that you should go for the treatment or not. If you passed by it, our doctor will send you an online prescription, by which you are able to purchase medicine online which one is mentioned in prescription. There is no harassment to run to doctor’s clinic, and then go to medical shop. You can solve it by sitting in your place only.
What is male hair loss or male pattern baldness or androgenic alopecia
The most common type of hair loss is Male hair loss. It is caused by increased sensitivity to male sex hormones (androgens) in certain parts of the scalp, and is passed on from generation to generation.
In the past, baldness was often seen as something unfortunate or undesirable. However, this attitude has changed over the years and nowadays a clean-shaven head is usually considered both fashionable and attractive.
The condition usually starts in men aged 20 to 30 and follows a typical pattern. First, a receding hairline develops, and gradually the hair on top of the head also begins to thin. Eventually, the two balding areas meet to form a typical U-shape around the back and sides of the head. The hair that remains is often finer, and does not grow as quickly as it used to.
How is male hair loss treated?
Baldness is generally regarded as natural. So if a person decides they wish to try to get their hair back, they will probably have to pay for the lengthy, expensive procedure themselves.
Treatment with medication
Finasteride (Propecia) is a medicine taken in tablet form that partially blocks the effects of the male hormones (an ‘anti-androgen’). It is used in a higher dose to reduce the size of the prostate gland in men with benign prostatic hypertrophy. Propecia has been shown to halt further hair loss and promote re-growth of scalp hair in approximately 80 per cent of patients after three to six months. Treatment must be continued to sustain the improvement in hair growth. It is only available on private prescription.
Hair Loss in men is a very common factor in today’s world. To fight against Hair loss in men or male pattern baldness the treatment is available online. Online Hair Loss Treatment is a very fast and effective way for male pattern baldness.
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Hair loss affects up to 80% of men and 50% of women, and in most cases androgenetic alopecia is to blame. This article explains how Skull Expansion is the true cause of hair loss and why the conventional reasons given to explain it are wrong!
There’s no doubt that male sex hormones (androgens) somehow cause hair loss in those with the genetic predisposition towards it. Furthermore, dihydrotestosterone (DHT) is the androgen directly linked to this process.
However, genetics and male sex hormones do not fully explain the exact mechanism that will cause hair loss to start. That’s because they can’t answer the following questions:
Q1. Why do some people lose hair from the front (receding temples), the back (a bald patch), or both these regions of the scalp?
Q2. Why is it that hair can fall faster in one region of the scalp than it does in the other, and start at different times in a person’s life? (E.g., about 20% of men start losing their hair at puberty but most don’t start until they’re much older).
Q3. How can DHT be linked to both hair loss and hair growth? (DHT will, during puberty, stimulate hair to grow in other parts of the body).
These are all very relevant questions about the hair loss process. So, it’s important that complete and accurate answers are given before any theory can be acknowledged as the true underlying cause of androgenetic alopecia.
It now seems more likely that the actual mechanism that causes this type of hair loss is Skull Expansion. Here’s a very brief explanation of how this process causes genetic hair loss:
When you’re growing up into an adult, your skeleton obviously gets bigger and bigger. This, of course, includes the skull, which not only grows in size but also changes shape.
Once you reach adulthood, this process (called bone remodelling and resorption) then continues throughout life. For some, this simply involves maintenance of the bones (i.e., keeping them strong and healthy). But, for those who suffer hair loss, this process will cause the frontal and parietal bones of the skull to grow.
This is Skull Expansion, and is the direct cause of hair loss within the male pattern baldness (MPB) region of the scalp.
The genetic link to male pattern baldness is due to the skull shape you inherit. Different skull shapes will have different growth potential (this simply means that the predisposition towards Skull Expansion will vary). The extent to which you lose hair is directly related to the extent to which your skull will expand. Obviously this means that greater Skull Expansion will cause more hair loss.
Only Skull Expansion can provide answers to all of those earlier questions:
A1. Hair loss at the front is caused by Skull Expansion of the frontal bone. A bald patch at the back is caused by Skull Expansion of the parietal bones. And hair loss at the front and back of the scalp simultaneously, is caused by Skull Expansion of both frontal and parietal bones.
A2. The different rates of hair loss between the front and back of the scalp depend upon the skull shape you inherit and its growth potential. That’s why your hair loss could start as early as puberty or much later on in life.
A3. DHT can stimulate hair growth, but it also encourages bone growth. Androgens like DHT are steroid hormones which have an anabolic effect on bone formation (i.e., they make it grow!) DHT causes Skull Expansion, which then causes hair loss to start.
So, now you know that the true cause of genetic hair loss is Skull Expansion. And, should you be in any doubt, why not simply contact a hair specialist, ask those questions, and see what answers you get!
For further illustrated details about the Skull Expansion process, visit www.top-hair-loss-remedy.com/hair-loss.html
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Hair loss affects up to 80% of men and 50% of women, and in most cases androgenetic alopecia is to blame. This article explains how Skull Expansion is the true cause of hair loss and why the conventional reasons given to explain it are wrong!
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Male pattern hair loss is the most common form of hair loss. Male pattern baldness can be embarrassing and causes many men to feel uncomfortable and insecure. It representing close to 95% of all cases of hair loss in men. And about half of all men experience male pattern hair loss by age 50. In male-pattern baldness, hair loss typically results in a receding hair line and baldness on the top of the head. Male Pattern Baldness is becoming a major health issue for most of the developed nations. In the UK, the population of men directly suffering from this disorder is constantly growing. So if you have male pattern hair loss, you are certainly not alone and there are male pattern baldness treatments available. Read on to learn about a medical treatment that has helped to treat male pattern baldness.
Male pattern baldness or Androgenic Alopecia
Male pattern baldness affects most men at some stage. Male hair loss is the most common type of hair loss. About three in ten 30 year olds and half of 50 year olds are quite bald. Typically, at first the hair begins to recede (thin) at the front. At the same time, the hair usually becomes thin on the top of the head. A bald patch gradually develops in the middle of the scalp. The receding front and the bald patch on the top gradually enlarge and join together. A rim of hair is often left around the back and sides of the scalp. In some men, this rim of hair also thins and goes to leave a completely bald scalp. It is typically a progressive condition left untreated the hair loss will likely continue. Treatment can usually prevent further hair loss, and often cause hair re-growth.
Reasons behind Male pattern baldness
Hair is made in hair follicles which are like tiny pouches just under the skin surface. Some men have areas on the scalp that are extremely sensitive to the male sex hormones that circulate in men’s blood. The hormones make the hair follicles shrink from where the hair grows. After a while, they become so small that they can’t replace lost hairs. A hair normally grows from each follicle for about 3 years. It is then shed, and a new hair grows from the follicle. This cycle of hair growth, shedding, and new growth goes on throughout life. The level of testosterone, the main male hormone, is normal in men with baldness. Hair follicles convert testosterone into another hormone called dihydrotestosterone.
Effects of male pattern baldness
Despite being a very common condition male pattern baldness can have a serious effect on the sufferer. Male pattern baldness can led to a poor body image, make people feel old and unattractive and in general have low self-esteem. This leads to a greater likelihood of depression and other psychological problems. In general first impressions are very important and having male pattern baldness can strongly affect whether or not a man perceives himself as attractive to others. If left untreated, male pattern baldness (androgenetic alopecia) will tend to get worse with time. This will happen at different rates for different people.
Treatment Options for Male pattern baldness
Doctors tell you a common conventional treatment for male pattern baldness is Propecia (Finasteride). Propecia is the only prescription tablet in the UK for male pattern baldness. Finasteride was launched in the UK in 2002, although it has been available in the US since 1997. Propecia is commonly prescribed for androgenetic alopecia, which works by inhibiting 5-alpha-reductase. Oral finasteride has to be taken once daily for three months before its benefits can be noticed.
Propecia Male Pattern Baldness Pills
Mild to moderate Male Pattern Hair Loss affects about 50% of men by age 50. PROPECIA, available only by prescription, is only option to treat male pattern hair loss. PROPECIA blocks the formation of DHT and in this way appears to interrupt a key factor in the development of inherited male pattern hair loss in men.
It works by blocking the conversion of testosterone to dihydrotestosterone. The hair follicles are then not affected by this hormone, and can enlarge back to normal.
Propeciafinasteride.co.uk is able to offer individuals afflicted with Male Pattern Baldness an evaluation for suitability to Propecia treatment. The evaluation is performed by qualified doctors in a manner which is simple, secure, and without embarrassment.
How Propecia Work?
Hair re-growth occurs in about 2 in 3 men who take a Propecia (finasteride) tablet each day. Most do not have any further hair loss whilst taking finasteride. It has no effect in about 1 in 100 men. So, if you take finasteride, you have a good chance of hair growth. Some points about finasteride include the following. It takes about 4 months for any effect to be noticed and up to 1-2 years for full hair growth. Side-effects are uncommon. The most common is that about 2 in 100 treated men report loss of sex drive (libido). It does not work in women with male pattern baldness.
Why to deal Male Pattern Baldness on the Internet?
For many men who are prescribed treatments for male pattern baldness, taking their prescription to the pharmacy represents an embarrassing and inconvenient hurdle which some may not overcome. By communicating the problem to our physicians online you’ll avoid personal embarrassment. Our physicians can prescribe Propecia based upon your medical history.
Propeciafinasteride offers an online alternative. Patients must complete a questionnaire which will be reviewed by our physicians. If the physician approves the patient’s use of Propecia, we will deliver to your chosen delivery address, so there is no need to go into a pharmacy.
Male pattern baldness is caused by many and now it is possible to treat male pattern baldness. The treatment for Male Pattern Baldness is also available online. Learn some possible solutions on how to treat male pattern baldness and how to stop feeling self conscious about losing your hair.
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