Posts Tagged ‘Hereditary Baldness’
The definition of beauty in a woman has always included healthy hair. As a woman, hair loss can have a particularly damaging effect on the way that you perceive yourself. Hair loss in women may be caused by factors ranging from hormonal imbalances to hereditary baldness.
You may witness a thinning of your hair after a major operation. An illness can cause hair loss because it interrupts the normal function of the body. The hair that is lost in the course of an illness is usually grown back after you recover from the illness.
Hair loss can range from minimal to catastrophic. Cicatricial Alopecia is a hair loss condition that is on the scale of catastrophic because it causes patchy hair loss. A person who has Cicatricial Alopecia is bound to experience itching and pain in addition to the loss of hair.
When a teenager starts losing his or her hair, the causes are usually not far fetched. A teenager who is ill may start losing hair because of that illness. Some teenagers may start losing their hair because of emotional stress. But whatever you suspect the cause to me, see your doctor immediately for help.
As a male it’s worth knowing that baldness can begin in different patterns. You may start experiencing baldness as your hair recedes from the temples. For some men, baldness may start at the top of the head and recede down the sides of the head.
Hair loss can be extensive in scale in the sense that it can influence the hair on your body. Hair loss is a condition that affects roughly one third of women and men in America. For some people, the loss of their hair may be a permanent condition.
New methods of treating hair loss keep on popping up on a daily basis. Follicular unit transportation is a treatment that involves a patch that is taken from the back of the head and placed on the bald patch. The follicular unit transplant helps to solve the problem of balding.
Hair loss either in men or women can be an unpleasant experience. Hair loss needs not to be a looming problem for you because of the cures available. Hair loss affects a great deal of people in America.
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Hair loss can be caused by different factors but heredity is the number one reason why men and women lose their mane. Hereditary hair loss in men and women has the same leading cause, which is dihydrotestosterone (DHT) attacking our hair follicles. DHT is a metabolite of the male hormone testosterone but it is also available in the female body. Men and women lose their hair not because of increased levels of DHT in their bodies but due to the susceptibility of their hair follicles to DHT attacks, although the exact mechanism and reasons why certain hairs, mostly those on the top of the head, are more vulnerable to such attacks are not yet know.
The main difference between the male and female form of hereditary hair loss is in its shape. The male form has a characteristic horseshoe pattern whereas the female form is typically a diffuse thinning across the entire scalp and is thus less easily-recognised. The female form of hereditary baldness is, in its form, practically indistinguishable from hair loss caused by various other factors. The second most common reason for a woman to lose her hair is hormonal imbalances during and after pregnancy or menopause. Such changes are typically of a temporary nature and so also is the hair loss, although post-menopausal hair loss is in most instances permanent.
When it comes to treating hair loss in women there are a number of specifics. First, most women do not make very good candidates for hair transplantation due to their diffuse thinning pattern, which makes it impossible to clearly identify the hair that will be resistant to future miniaturisation. Secondly, finasteride, which is one of the only two FDA-approved hair loss treatments available today, cannot be used in women and neither can dutasteride, which is its closest and assumedly yet more powerful relative. Rogaine (generic name minoxidil) is the second FDA-approved hair loss treatment and its approved concentration for women is only 2% versus 5% for men. However, many doctors around the world recommend their female patients use male formulations of minoxidil, with a concentration of 5%, such as Rogaine foam. Aminexil is a molecule similar to minoxidil and it is often recommended to women who are pregnant or breastfeeding as a safer option than minoxidil.
Although some antiandrogens such as finasteride (better known as Propecia) or dutasteride cannot be prescribed to women, there are other antiandrogen medications that can be effectively used to treat baldness in women. Spironolactone (trade name Aldactone) and cyproterone acetate (used in contraceptives such as Diane 35, Diane 50 and Ginette 35) are antiandrogens most commonly used to treat female pattern baldness.
Another treatment with satisfactory rates of success is topical estrogen solutions such as Crinohermal, which use a female hormone, estradiol, as their main active ingredient. Estradiol is capable of inhibiting the conversion of testosterone into follicle-harming DHT. Hormone replacement therapy is another hormonal treatment suitable for women at menopause, with estrogens and progesterone pills and creams being the most common forms of treatment. Estrogen levels in the body decline with time. As women enter the menopause, estrogen levels decline and thus more of the male hormone testosterone is then available to be converted into follicle-harming DHT.
The above list of treatments for female pattern hair loss is not exhaustive, though. A number of other remedies exist that are often claimed to help promote hair growth in women, such as ketoconazole, fluridil, flutamide, alfatradiol, as well as numerous substances of natural origin. Despite the fact that there are female patients who will swear by some of these treatments, none of them has ever been sufficiently clinically tested, let alone approved by any major national health supervisory authority as a treatment for female hair loss and the claims of their guaranteed effectiveness should be taken with a grain of salt.
When it comes to treating hair loss in women there are a number of specifics. First, most women do not make very good candidates for hair transplantation due to their diffuse thinning pattern. Secondly, finasteride, which is one of the only two FDA-approved hair loss treatments available today, cannot be used in women and neither can dutasteride, which is its closest and assumedly yet more powerful relative.
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When it comes to dealing with hair loss, it is medicinal pills and topicals that spring to most peoples’ minds as the options holding the greatest promise. There are also other available treatment options, such as surgical and non-surgical hair replacement, but to date only oral and topical medicinal treatments have been proven to reduce and reverse hair loss naturally. Hair transplantation surgery, though providing the best cosmetic results, cannot slow or reverse hair loss. Natural and herbal hair loss treatments try to mimic medicinal treatments in their mode of action but their effectiveness in treating hair loss has never been confirmed in any relevant clinical study and many of them are associated with hair scams.
The two medicinal treatments that have been approved by the FDA (Food and Drug Administration) in the US for treating hair loss are topical minoxidil (trade name Rogaine) and oral finasteride (Propecia). These two hair loss drugs have been also approved by national health supervisory authorities in many other countries. Topical minoxidil is suitable for both sexes, whereas finasteride can only be prescribed to male patients. Minoxidil is a vasodilator, originally used to treat high blood pressure, which was later found to possess hair growth stimulating properties when applied topically to the scalp. However, its mechanism of action is not exactly known.
Finasteride is an antiandrogen that was first applied to treat prostate enlargement, also known as benign prostatic hyperplasia (BPH). It acts by inhibiting conversion of the male hormone testosterone to the follicle harming didydrotestosterone (DHT). The discovery of finasteride’s positive effects on hair growth led to finding the true cause of hereditary baldness, which are the harmful attacks of DHT on our hair follicles. Since making this discovery, a search for other alternative DHT blockers has begun, especially amongst antiandrogen drugs and herbs that have, in the past, been used to treat urinary problems.
Dutasteride (trade name Avodart) is a drug similar to finasteride and has been studied extensively for treating hair loss. It is currently undergoing phase III clinical testing. Dutasteride (Avodart) has been approved for treating BPH and is thus available in pharmacies in many countries around the world. Although it has not yet been approved for hair loss by any national health supervisory authority, it is being prescribed by some clinics and doctors to male hair loss patients who no longer respond to finasteride. Dutasteride is held by many doctors and patients to be a more powerful hair loss drug than finasteride but also with more severe side effects.
Flutamide (trade name Eulexin) is powerful antiandrogen used to treat prostate cancer. It works by binding to the androgen receptors where it competes with DHT. Oral use of this drug can cause serious side effects but it is believed that topical applications might have less adverse side effects and could be, in the future, used to treat hereditary hair loss. Nonetheless, more research is needed to verify such claims.
Spironolactone (trade name Aldactone) is another antiandrogen that acts by binding to androgen receptors, competing with DHT. It is used in women to treat acne, hair loss and hirsutism (excess body hair) and although there are some generic topical applications out there for treatment of male pattern baldness containing spironolactone, it has never been approved to treat hair loss in men and should better be avoided.
Aminexil, was developed by L’Oreal to treat baldness in men and women and its molecule seems to be very similar to that of minoxidil. Its mechanism of action is not exactly known and it is considered to be a less powerful weapon in the fight against hair loss than minoxidil.
The most promising novel drug currently under development is called NEOSH101. It happens to be in phase II clinical trials and is supposed to be a hair growth stimulant, distantly related in its actions to minoxidil. Although not expected to become an ultimate cure for baldness, it could improve the chances of hair loss sufferers of regrowing some of their lost hair as it is believed to be a stronger hair growth stimulant than minoxidil.
The above list of medicinal treatments for hair loss is not exhaustive. There are some other drugs that are believed to help treat hair loss, such as superoxide dismutase, alfatradiol, fluridil, ketoconazole, etc. but none of them has ever been proven in any serious clinical study to promote hair growth and more studies will be needed to evaluate their positive effects on hair loss. Therefore, for the time being, minoxidil and finasteride remain the main weapons in the fight against genetically-determined hair loss conditions in male patients.
When it comes to dealing with hair loss, it is medicinal pills and topicals that spring to most peoples’ minds as the options holding the greatest promise. There are also other available treatment options, such as surgical and non-surgical hair replacement, but to date only oral and topical medicinal treatments have been proven to reduce and reverse hair loss naturally.
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